HFE 3 Mutation Panel, HFE MSQ 1.1

For in vitro diagnostic use. Intended for professional use only.

Hemochromatosis (HH) is a prototypical disorder of iron metabolism and is an autosomal recessive inherited iron metabolism disease.

HH leads to progressive iron accumulation in various parenchymal organs. Hemochromatosis can be classified as primary (hereditary) or secondary hemochromatosis. Autosomal recessive form representing a condition where iron absorption from the intestines is increased, and there is no underlying secondary disease. Mutations in the Hemochromatosis gene (HFE) allow for detection through screening before the symptoms of the disease develop. Hereditary Hemochromatosis is typically characterized by mutations in the HFE gene, specifically C282Y and/or H63D.

FEATURES

Fast and User-Friendly with Multiplex Mini Sequencing PCR Technology
High Sensitivity
CE-IVD (Conformité Européenne - In Vitro Diagnostic)

DATA INTERPRETATION

Figure 1: Genemapper image of HFE 3 Mutations Panel

ORDER INFORMATION

CATALOG NO	01031025: HFE 3 Mutations Panel, HFE MSQ 1.1 (25 Tests)
	01031050: HFE 3 Mutations Panel, HFE MSQ 1.1 (50 Tests)
	01031100: HFE 3 Mutations Panel, HFE MSQ 1.1 (100 Tests)
SAMPLE TYPE	Whole Blood with EDTA tube
TEST CONTENT	HFE Primer Mix, HFE MSQ Mix, PCR Master Mix, DMSO, Taq DNA Polymerase, ddH2O, EXO I, SAP, SNaPshot Mix
TARGET GENE and LOCI	H63D (c.187C>G), C282Y (c.845G>A), HFE S65C (c.193A>T)
STORAGE CONDITIONS and SHELF LIFE	Should be stored at -20 °C in the dark. Shelf life is 12 months.
COMPETIBLE DEVICES	All PCR devices, ABI 3130, 3500 and other Genetic Analyzers