Beta Thalassemia Sequencing Panel, BT SQ 1.1

For in vitro diagnostic use. Intended for professional use only.

"Beta Thalassemia HBB Gene Deletion Duplication Analysis Laboratory Test" is the name of a genetic test used in the diagnosis of Beta Thalassemia disease. This test is performed to detect structural changes such as possible deletions (lack of gene segments) and duplications (excess of gene segments) in the individual's HBB (hemoglobin beta) gene.

Beta thalassemia is a blood disorder that occurs due to mutations in the HBB gene. These mutations can affect the normal function of the gene and lead to abnormal hemoglobin production. Deletions and duplications are changes that occur in the gene's structure and can increase the risk of beta thalassemia.

This laboratory test conducts DNA analysis to detect possible deletions and duplications in the individual's HBB gene. Test results play a significant role in assessing the risk of beta thalassemia and can aid in understanding the genetic basis of the disease. Based on the test results, it can be determined whether an individual is a carrier of beta thalassemia or at risk of beta thalassemia major.

Overall, the Beta Thalassemia Sequencing Panel, with the BT SQ 1.1 Kit, plays a critical role in the diagnosis, risk assessment, and treatment planning of beta thalassemia. Test results can help individuals understand their health status and receive appropriate treatment guidelines.

FEATURES

It covers Exon 1-2-3, Intron 1-2-3, 5'UTR, 3'UTR, Poly A regions.
The kit has a wide coverage ability to detect various Beta Thalassemia variants and carrier states.
The Beta Thalassemia Sequencing Kit serves as an important tool for healthcare professionals and researchers in the diagnosis and management of genetic diseases. With rapid results, precise diagnoses, and broad coverage, this kit helps improve the quality of life for beta thalassemia patients and provides important information for carriers.
Reliable results are ensured using high-quality reagents and equipment.
Treatment plans for beta thalassemia patients can be personalized based on the patient's genetic profile.

DATA INTERPRETATION

Figure 1: Electropherogram image obtained from the ABI 3500 Genetic Analyzer of the Beta Thalassemia Sequencing Panel, BT SQ 1.1 kit.

ORDER INFORMATION

CATALOG NO	SQHLKSBT01-25: Beta Thalassemia Sequencing Panel, BT SQ 1.1 (25 Tests)
	SQHLKSBT01-50: Beta Thalassemia Sequencing Panel, BT SQ 1.1 (50 Tests)
	SQHLKSBT01-100: Beta Thalassemia Sequencing Panel, BT SQ 1.1 (100 Tests)
SAMPLE TYPE	EDTA-treated Whole Blood in Tube
TEST CONTENT	HBB Gene 1st Amplicon Forward and Reverse Primers, HBB Gene 2nd Amplicon Forward and Reverse Primers, HBB Gene 1st Amplicon Forward Primer, HBB Gene 1st Amplicon Reverse Primer, HBB Gene 2nd Amplicon Reverse Primer, HBB Gene 2nd Amplicon Forward Primer, HBB Gene 2nd Amplicon Reverse Primer, dNTP Mix, 10x PCR Buffer, MgCl2
TARGET GENES and POINTS	All of the HBB genes
STORAGE CONDITIONS and SHELF LIFE	Should be stored at -20 °C in the dark. Shelf life is 12 months.
COMPATIBLE DEVICES All PCR Devices	All PCR devices, ABI 3130, 3500, and other genetic analyzers